Glucoraphanin

Glucoraphanin

is one of the glucosinolates.
glucoraphanin is mainly found in cruciferous vegetables, such as radish, broccoli, kale, raisin and so on.
glucoraphanin is an important secondary metabolite in cruciferous plants with anticancer, antioxidant and antibacterial activities.
Glucosinolates, or glucosinolates for short, are secondary metabolites rich in nitrogen and sulfur in plants. Glucosinolates and their derivatives (isothiocyanates, thiocyanates, and nitriles) have special roles in plant defense reactions, special flavor formation, and anticancer. Glucosinolates can be divided into aliphatic, aromatic and indole glucosinolates according to the amino acid source of side chain R.
The degradation products of glucoraphanin (4-methylsulfinylbutenyl glucosinolate) are mainly sulforaphane (Sulforaphane), sulforaphane nitrile (Sulforaphane nitrile), oxazolidinethione (Goitrin) , 3-methyl sulfoxide-based isothiocyanate (Iberin) is the main, and the highest content is sulforaphane.
4-Methylsulfinyl butyl glucoside, also known as glucoraphanin, belongs to aliphatic glucosinolate, and its degradation product is sulforaphane.

Sulforaphane has great anticancer activity and is a multifunctional inducer that can induce the body to produce type II detoxification enzymes – glutathione transferase and quinone reductase. to anticancer effect.

In 2015, American manufacturers submitted an application to China to list “broccoli seed extract as a new food raw material”; in 2016, broccoli seed extract passed the GRAS (Generally Recognized as Safe) certification of the U.S. Food and Drug Administration; In 2017, the Chinese National Health and Family Planning Commission approved the water extract of broccoli seeds containing 13-20% of glucoraphanin as a new food raw material (No. 7 document of 2017), so that the water extract of broccoli seeds was officially included in the food raw material library. It marks that glucoraphanin can be widely used in the field of Chinese food and contribute to public health!